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DPPH Radical-scavenging Effect of Several Phenylpropanoid Compounds and Their Glycoside Derivatives
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- TOMINAGA Hitoshi
- Department of Biotechnology and Chemistry, School of Engineering, Kinki University
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- KOBAYASHI Yuka
- Department of Biotechnology and Chemistry, School of Engineering, Kinki University
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- GOTO Takashi
- Cow Brand Soap Co., Ltd.
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- KASEMURA Kazuo
- Pharmaceutical, Tamura Co., Ltd.
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- NOMURA Masato
- Department of Biotechnology and Chemistry, School of Engineering, Kinki University
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Description
Eugenol, isoeugenol, caffeic acid, ferulic acid, isoferulic acid, estragole, trans-anethole, and paeonol are components of a Chinese herbal medicine used as a painkiller and stomachic. We investigated the potential role of these compounds as antioxidants. We studied the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical-scavenging effect of these molecules, together with some glycoside derivatives, to ascertain their potential in reducing the levels of activated oxygen species in vivo. The DPPH radical-scavenging effects of eugenol, isoeugenol, and the glycoside derivatives of caffeic acid, ferulic acid, and isoferulic acid (SC50=8—28 μM) were similar to those of α-tocopherol, which was used as a positive control.<br>
Journal
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- YAKUGAKU ZASSHI
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YAKUGAKU ZASSHI 125 (4), 371-375, 2005
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390001206128579840
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- NII Article ID
- 10016428435
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- NII Book ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL BIB ID
- 7311057
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- PubMed
- 15802883
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed