ミオシンとチュブリンの相互作用におけるATPの影響

DOI Web Site Web Site

書誌事項

タイトル別名
  • Effects of ATP on the Interaction of Myosin with Tubulin
  • ミオシン ト チュブリン ノ ソウゴ サヨウ ニ オケル ATP ノ エイキョ

この論文をさがす

抄録

In regard to the interaction between myosin and tubulin, it has become apparent that ATP reduced the binding amount of tubulin to myosin when myosin was preincubated with ATP as reported by Hayashi et al. The effect of this decrease on both the turbidity change of actomyosin by ATP and actin-activated myosin Mg-ATP ase activity was investigated by the addition of ATP ; These inhibitions caused by tubulin were smaller in the case of preincubation of myosin with ATP than that with tubulin. Tubulin inhibited the actin-activated myosin Mg-ATP ase activity when myosin, actin, and ATP were mixed after the incubation. Actin provided a better protection than ATP against the inhibition by tubulin. The addition of actin and ATP after myosin was bound to tubulin resulted in no change in either inhibition level. These results suggest that ATP has an important role in the interaction between myosin and tubulin.

収録刊行物

  • 薬学雑誌

    薬学雑誌 101 (9), 848-851, 1981

    公益社団法人 日本薬学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ