Effect of Crude Drugs on Experimental Liver Damages I. The Active Principle of Zedoariae Rhizoma

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Other Title
  • 実験的肝障害に対する生薬の活性成分(第1報)ガジュツの活性成分について
  • 実験的肝障害に対する生薬の活性成分-1-ガジュツの活性成分について
  • ジッケンテキ カン ショウガイ ニ タイスル ショウヤク ノ カッセイ セイブ

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Abstract

Measurement of thiopental sodium-induced sleepig time was carried out as a parameter for the determination of the effectiveness of antihepatotoxic substances on liver damage induced by carbon tetrachloride. New sesquiterpenoid"Furanogermanone"isolated from the hexane extractive of "Zedoariae Rhizoma (on the goods from China)"prevented the prolongation of the sleeping time in mice caused by the administration of CCl4 and the increase in serum GOT, GPT and LDH levels.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 102 (3), 306-309, 1982

    The Pharmaceutical Society of Japan

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