Effects of Aloe Extracts, Aloctin A, on Gastric Secretion and on Experimental Gastric Lesions in Rats

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Other Title
  • Aloe抽出成分Aloctin Aのラットの胃液分泌及び各種実験胃損傷に対する効果
  • Aloe抽出成分Aloctin Aのラット胃液分泌及び各種実験胃損傷に対する効果
  • Aloe チュウシュツ セイブン Aloctin A ノ ラット イエキ ブン

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Description

Effects of aloctin A, glycoprotein isolated from leaves of Aloe arborescens MILL, on gastric secretion and on acute gastric lesions in rats were examined. Aloctin A given intravenously dose-dependently inhibited the volume of gastric juice, acid and pepsin output in pylorus-ligated rats. Aloctin A given intravenously significantly inhibited the development of Shay ulcers and indomethacin-induced gastric lesions in rats. It also inhibited water-immersion stress lesions induced in pylorus-ligated rats.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 109 (5), 335-339, 1989

    The Pharmaceutical Society of Japan

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