Water of Crystallization in Disodium 5'-Inosinate and Disodium 5'-Guanylate and Their Mixed Crystal Formation

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Other Title
  • 5'-イノシン酸ナトリウムおよび5'-グアニル酸ナトリウムの結晶水の性質と混晶
  • 5 -イノシンサン ナトリウム オヨビ 5 -グアニルサン ナトリウム ノ ケッショウスイ ノ セイシツ ト コンショウ

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Abstract

Properties of water of crystallization in disodium 5'-inosinate (I) and in-(II) and-form (II') of disodium 5'-guanylate were investigated by means of thermogravimetric analysis, differential thermal analysis, X-ray diffraction, moisture equilibium, and dielectric relaxation measurements. Their results show that these crystals contain eight, seven, and four molecules of water of crystallization, respectively and that the properties of these water molecules in I and II are similar. Ability to form a mixed crystal having various composition was also found.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 87 (12), 1436-1441, 1967

    The Pharmaceutical Society of Japan

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