A New Synthesis of 1-(m-Methoxyphenyl)-2-propanone.

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Other Title
  • 1-(m-Methoxyphenyl)-2-propanoneの合成
  • 1- m-Methoxyphenyl -2 propanone ノ ゴウセイ

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Abstract

Phenyl ether of eugenol was reduced with metallic sodium in liquid ammonia to give 1-(m-methoxyphenyl)-1-propene (III). Synthesis of 1-(m-methoxyphenyl)-2-propanone (VI) from (III) via 1-(m-methoxyphenyl)-2-nitro-1-propene was examined. The reaction of performic acid with III followed by treatment with acid also gave VI, though in an unsatisfactory yield.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 87 (11), 1419-1422, 1967

    The Pharmaceutical Society of Japan

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