Syntheses of Aspidium Constituents and Similar Compounds. IV.

DOI Web Site

Bibliographic Information

Other Title
  • メンマ有効成分とその類似構造化合物の合成 (第4報)
  • フィリチン酸のアシル誘導体フィリチン酸ブタノン, アルバスピジン等の合成
  • Synthesis of Acyl Derivatives of Filicinic Acid (Filicinic Acid Butanone, Albaspidin, etc.)

Abstract

Filicinic acid was prepared in a comparatively good yield by the modified Robertson method and the application of aluminum chloride, nitrobenzene, and carbon disufide with acid anhydride to filicinic acid afforded butyroyl-, isovaleroyl-, and hexanoyl-filicinic acids (Table I). The condensation of these acids with formaldehyde yielded albaspidin, i.e. methylene-bis (butyroylfilicinic acid), m.p. 149.5-150°. Methylene-bis (isovaleroyl- and hexanoylfilicinic acids), m.p. 121-122° and 131-132°, were prepared by the same procedure.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 76 (11), 1258-1260, 1956

    The Pharmaceutical Society of Japan

Keywords

Details 詳細情報について

Report a problem

Back to top