2-ヒドロキシトリプトフォールの合成

書誌事項

タイトル別名
  • Synthesis of 2-Hydroxytryptophol
  • 2 ヒドロキシトリプトフォール ノ ゴウセイ

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抄録

Attempted synthesis of 2, 3-dihydrofuro[2, 3-b]indole from α-(o-nitrophenyl)-γ-butyrolactone was found to give 2-hydroxytryptophol in stead of the objective compound. 2-Hydroxytryptophol is a novel compound and several of its derivatives were synthesized ; 3-(1-ethyl-2-hydroxyethyl)oxindole (XV), 3-(2-ethyl-2-hydroxyethyl)oxindole (XVI), and 3-(2, 2-dimethyl-2-hydroxyethyl)oxindole (XVII). Several novel α-phenyl-α-butyrolactone derivatives and their novel α-nitro- and aminophenyl derivatives were also synthesized ; α-(o-and p-nitrophenyl)-γ-butyrolactone (VI), α-(o-and p-nitrophenyl)-γ-ethyl-γ-butyrolactone (VIII), α-(p-aminophenyl)-α-ethyl-γ-butyrolactone (XI), α-(p-aminophenyl)-γ-ethyl-γ-butyrolactone (XII), and α-(p-aminophenyl)-γ, γ-dimethyl-γ-butyrolactone (XIII).

収録刊行物

  • 薬学雑誌

    薬学雑誌 95 (6), 710-714, 1975

    公益社団法人 日本薬学会

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