Reactions of 4-Amino-or 4-Hydroxyaminoquinoline 1-Oxide and Their Related Compounds with POCl<SUB>3</SUB>

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Other Title
  • 4-Amino-および4-Hydroxyaminoquinoline 1-Oxide関連化合物とPOCl<SUB>3</SUB>との反応
  • 4-Amino-および4-Hydroxyaminoquinoline1-Oxide関連化合物とPOCl3との反応
  • 4 Amino オヨビ 4 Hydroxyaminoquinoline1 Ox

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Description

The reaction 4-aminoquinoline 1-oxide (4-AQO) or 4-hydroxyaminoquinoline 1-oxide (4-HAQO) with POCl3, and its mechanism were examined, and it was found that the reaction of 4-AQO, 4-HAQO, or their derivatives with POCl3 afforded the corresponding 3-chloro compound as the main product. A reaction mechanism was proposed for the formation of the 3-chloro compound from 4-AQO and 4-HAQO.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 96 (6), 725-731, 1976

    The Pharmaceutical Society of Japan

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