Rubella Seroprevalence among the General Population in Dongguan, China
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- Lin Weiyan
- Department of Epidemiology and Biostatistics, Guangdong Medical College
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- Wang Dong
- Department of Immunization Program, Dongguan Center for Disease Control and Prevention
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- Xiong Yongzhen
- Department of School Clinic, Guangdong Medical College
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- Tang Hao
- Department of School Clinic, Guangdong Medical College
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- Liao Zhengfa
- Department of Epidemiology and Biostatistics, Guangdong Medical College
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- Ni Jindong
- Department of Epidemiology and Biostatistics, Guangdong Medical College
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Abstract
In order to assess the immunity to rubella infection in Dongguan, China, we conducted a seroprevalence survey on rubella and used ELISA to measure rubella-specific IgG in serum samples. A total of 1,017 individuals aged 0–59 years were selected by multistage cluster sampling. Among them, 904 (88.9%) were seropositive for rubella. Two groups (20–29 and ≥40 years) had seropositivity rates of <90%. In comparison with participants aged ≥20 years, rubella immunization rates were higher in those aged <20 years (83.2% vs. 93.7%, respectively; χ2 = 28.063, P < 0.001). Among women aged 20–29 years, only 63.8% had antibodies above the protective level. Multivariate analysis revealed that only sex and age were significantly associated with rubella-protective antibody levels. Our results suggest that in the study area, women of childbearing age had a greater serological susceptibility to rubella. Additional vaccinations for rubella of susceptible young adults should be considered, particularly in women of childbearing age.
Journal
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 68 (3), 192-195, 2015
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
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Keywords
Details 詳細情報について
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- CRID
- 1390001206240110720
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- NII Article ID
- 130005070801
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- NII Book ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL BIB ID
- 026408103
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- PubMed
- 25672349
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed