FORMATION OF SOLUBLE FIBRINOGEN-FIBRIN COMPLEX IN LIQUID HUMAN PLASMA; REFLEXION OF COAGULATION PROCESS IN STORAGE
書誌事項
- タイトル別名
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- Formation of Soluble Fibrinogen Fibrin
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Analysis was performed on a high-molecular fraction with fibrinogen antigenicity present in Liquid Human Plasma. This fraction, although seemed to resemble macromolecular FDP (fibrinogen degradation product) derived from stabilized fibrin, has many features not shared with the latter:<BR>1) This fraction is sensitive to sodium dodecylsulfate (SDS) treatment.<BR>2) Degradation products of this fraction obtained by digestion with plasmin, when eluted from a column of Sephadex G-200, exhibited a single peak of FDP-D antigenicity at the position of D-monomer.<BR>3) In SDS polyacrylamide gel electrophoresis in the presence of dithiothreitol (DTT), no evidence for the presence of γ-dimer was obtained.<BR>Thus, it is unlikely that the high-molecular fraction is formed through interchain cross-linking between fibrinogen molecules. The formation of the highmolecular complex was discussed in relation to coagulation process in stored plasma.
収録刊行物
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- Ｊａｐａｎｅｓｅ Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｂｉｏｌｏｇｙ
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Ｊａｐａｎｅｓｅ Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｂｉｏｌｏｇｙ 30 (2), 91-99, 1977
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390001206240489088
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- NII論文ID
- 130003953248
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- NII書誌ID
- AA1132885X
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- COI
- 1:CAS:528:DyaE2sXltFGnurs%3D
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- ISSN
- 18842828
- 00215112
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- NDL書誌ID
- 1819883
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- PubMed
- 916354
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可