Prevalence of the M Protein Gene in Group C and Group G Streptococci Isolated from Patients in Thailand

DOI Web Site Web Site PubMed 参考文献17件
  • Srifuengfung Somporn
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Tribuddharat Chanwit
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Sapcharoen Suwandee
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Nitayanon Perapon
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University

この論文をさがす

説明

We surveyed group C and group G β-hemolytic streptococci for emm and emmL (emm -like) genes which encode the M protein, as well as determined their antimicrobial susceptibilities. A total of 97 isolates 79 GCS/GGS isolates and 18 isolates from other groups were tested for the M protein gene by PCR. Focusing on invasive infections with group A (GAS), group C (GCS), and group G (GGS) β-hemolytic streptococci isolated from blood, the M protein gene was found in 90.0%, 84.6%, and 78.3% of isolates, respectively. The hypervariable N terminal region of the emm was sequenced from 62 isolates, and 26 types of the emm gene were identified. Based on these results, type emm222.2 may be endemic to Thailand. The results of antimicrobial susceptibility testing of groups C, G, and non-groups A to G isolates indicated high susceptibility (range 82–100%) to penicillin, cefotaxime, chloramphenicol, clindamycin, erythromycin, linezolid, ofloxacin, and vancomycin, whereas the isolates showed low susceptibility (range 0–15.6%) to tetracycline.

収録刊行物

参考文献 (17)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ