耳科領域, とくに慢性中耳炎病巣のGram陰性桿菌の推移と薬剤耐性

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タイトル別名
  • CHANGES OF THE GRAM-NEGATIVE FLORA IN CHRONIC OTITIS MEDIA AND THE DRUG SENSITIVITY PATTERNS
  • ジカ リョウイキ , トクニ マンセイ チュウジエン ビョウソウ ノ Gram インセイカンキン ノ スイイ ト ヤクザイ タイセイ

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The authors studied on the rates of isolation and drug sensitivities of Gram-negative bacilli isolated from the chronic otitis media during the period from 1966 to 1970.<BR>1. Gram-negative bacilli were isolated in the percentage of 25. 3, 19. 6, 61. 9, 56. 3, 36. 2 in each of the year 1966-1970, respectively.<BR>2. In the rates of isolation of each group, Ps. aeruginosa and Proteus showed a tendency of gradual decrease, whereas Moraxella showed a sudeen increase from 1968.<BR>3. Many strains of E. coli were found sensitive against AB-PC and CER, Proteus were sensitive against GM, AB-PC, CER and NA, and Ps. aeruginosa were sensitive against PLB, CL, and GM, while Moraxella were sensitive against PLB, CL and CB-PC.<BR>4. The peak of minimum inhibitory concentration distribution of FRM against Ps. aeruginosa and Moraxella were each 0. 19 and 12. 5 mcg/ml, that of GM were 0. 38 and 12. 5-50 mcg/ml respectively.<BR>Against CB-PC Moraxella were more sensitive than Ps. aeruginosa, the peak of the MIC distribution being 1. 56 mcg/ml, whereas in Ps. aeruginosa the peak was found 12. 5 mcg/ml.<BR>5. The majority of the strains of both Moraxella and Ps. aeruginosa was suppressed by CL and PLB, at the concentration below 6. 25 mcg/ ml.

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