Concentration of latamoxef of the fluid of simple renal cyst.

DOI

Bibliographic Information

Other Title
  • Ｌａｔａｍｏｘｅｆのじんのう胞内移行について

Abstract

The concentration of latamoxef (LMOX) into the fluid of simple renal cyst after one gram of intravenous administration was investigated in five patients. The bilateral renal function in all patients was normal on intravenous pyelography. The fluid of the cyst was aspirated percutaneously at 20 to 40 minutes after a bolus injection of the drug, serum and urine specimen a were got at the same time. The chemical analysis showed that the components of the cyst was nearly equal to that of the serum. The concentration of LMOX bioassayed using E. coli 7437 strain as a test organism revealed 0.46±0.154 μg/ml (mean±S. D.) in the fluid, 43±10.2 in serum, and 4, 100±2, 160 in urine. These results suggest, because of very low level of LMOX detected in the simple cyst, intravenous administration of antibiotics may not be effective to treatment for the patients with the disease.

Journal

  • CHEMOTHERAPY

    CHEMOTHERAPY 34 (4), 312-315, 1986

    Japanese Society of Chemotherapy

Details 詳細情報について

  • CRID
    1390001206279629696
  • NII Article ID
    130004195266
  • DOI
    10.11250/chemotherapy1953.34.312
  • ISSN
    18845894
    00093165
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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