尿路感染症に対するTicarcillinの臨床的検討

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タイトル別名
  • CLINICAL INVESTIGATION WITH TICARCILLIN IN URINARY TRACT INFECTION
  • ニョウロ カンセンショウ ニ タイスル Ticarcillin ノ リンショウ

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Ticarcillin was administered clinically to 18 cases of chronic complicated urinary tract infection, and the following results were obtained.<BR>1. Clinical efficacy was obtained in 12 cases out of 18 cases, efficacy rate being 66.7%. Classified by dose, no difference was observed on the effects, as both 2 g group and 4 g group showed an efficacy in 6 cases out of 9 cases, efficacy rate being 66. 7%. Classified by catheterization, efficacy rate was lower in catheterization group, as catheterization group showed an efficacy in 5 cases (55.6%) out of 9 cases, while non-catheterization group in 7 cases (77.8%) out of 9 cases.<BR>2. As to the bacteriological effects classified by bacterial species, Ps. aeruginosa disappeared in 8 strains out of 11 strains, disappearance rate being 72.7%, moreover even 7 CBPC resistant strains resulted in disappearance in 6 strains. In the cases of E. coli, all 4 strains disappeared, and 3 strains of them were ABPC resistant.<BR>3. As to the side effect of the drug, S-GOT was elevated in 2 cases, though a causal relation with the drug was unknown. No other side effect a symptom was observed, nor abnormality on laboratory tests.

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