外科領域におけるTicarcillinの基礎的;臨床的検討

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タイトル別名
  • BASIC AND CLINICAL EVALUATION OF TICARCILLIN IN SURGICAL FIELD
  • ゲカ リョウイキ ニ オケル Ticarcillin ノ キソテキ リンショウ

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1) The peak of serum and biliary level of ticarcillin following 3.0 g drip infusion were 166.0 and 100.0μg /ml respectively and the urinary excretion rate was 46.7% during 6 hours.<BR>2) Ticarcillin was applied to 9 infections and 4 cases for the purpose of protection of post operative infections in the surgical field. Some of cases were combined therapy with GM, DKB and CLDM. The effective rate was 84.6% (11/13).<BR>3) The daily dose was 6.0 g in 12 cases and 9.0-12.0 g in one case. The maximum total dose and duration were 186.0 g and 31 days respectively. No side effects were observed except a slight liver dysfunction after administration of ticarcillin was noticed in 1 case.

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