難治性尿性器感染症とTicarcillin

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タイトル別名
  • INTRACTABLE INFECTIONS OF URINARY TRACT TREATED BY TICARCILLIN
  • ナンジセイ ニョウ セイキ カンセンショウ ト Ticarcillin

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Ticarcillin was administered to 28 cases of intractable infections of urinary tract consisting of 15 cases of chronic complicated cystitis, 5 cases of acute pyelonephritis, 6 cases of chronic pyelonephritis and 2 cases of chronic epididymitis, and the following results were obtained.<BR>1) Global results were excellent effect in 11 cases, good effect in 9 cases, fair effect in 2 cases, and no effect in 6 cases, effective rate being 71. 4%.<BR>2) Classified the effect by dose, the drug was effective at 72. 2% of 18 cases to which a dose of 1 g was administered intramuscularly twice a day, and at 70. 0% of 10 cases to which a daily dose was increased to 3 6 g, and no difference was observed between both.<BR>3) Causative organisms were noticed by urine culture immediately before the drug administration in 23cases out of 26 cases of the infections of urinary tract, and these consisted of bacillus in 19 cases (82. 6%) and micrococcus in 4 cases. No clinical effect was observed in 5 cases (21. 7%), including 1 case of E. coli, 3 cases of Pseudomonas, and 1 case of Serratia. Pseudomonas was isolated in 8 cases, among which 5 cases (62. 5%) resulted in above good effect.<BR>4) As to the side effects which would have been attributed to the drug, no hypersensitivity and allergic reaction were observed, nor abnormal values were noticed in laboratory tests, except that induration and pain were encountered in 1 case, induration in 1 case, and pain in 1 case each after the intramuscular injection.

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