Ticarcillinにかんする基礎的・臨床的研究

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タイトル別名
  • LABORATORY AND CLINICAL USE OF TICARCILLLIN
  • Ticarcillin ニ カンスル キソテキ リンショウテキ ケンキュウ

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The antibacterial activity of ticarcillin (TIPC) and its therapeutic effectiveness in the infections of the field of obstetrics and gynecology were investigated and the following results were obtained.<BR>1) From the sensitivity test for clinical isolates of Staphylococcus aureus, Escherichia coli, Proteus mirabilis, Klebsiella and Pseudomonas aeruginosa, its antibacterial activity was found to be superior particularly in Ps. aeruginosa.<BR>2) The absorption of TIPC following 1.0g intramuscular or intravenous injection was comparatively good and also transference to fetus smooth. In particular, it was noticed that transference to amniotic fluid became higher with continuous administration.<BR>3) TIPC was used in 11 patients including intra-pelvic infections and urinary tract infections. As the result. the effective rate was 81. 8%.<BR>4) No noteworthy side effect was ohserved.

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