CLINICAL STUDIES ON TICARCILLIN

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  • TOMIOKA SUSUMU
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • KOBAYASHI YOSHIO
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • SUGIURA KOSAKU
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • AOKI MAKOTO
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • KIKUCHI MASAO
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • NEGISHI MASAYUKI
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • KANEKO SHOZO
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • SOTOYAMA KEISUKE
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine
  • HASEGAWA MITSUHITO
    Central Laboratories and Department of Internal Medicine Keio University, School of Medicine

Bibliographic Information

Other Title
  • Ticareillinに関する臨床的検討
  • Ticarcillin ニ カンスル リンショウテキ ケントウ

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Abstract

Clinical studies on ticarcillin, a new semisynthetic penicillin, were performed in the severe infections complicated with hemopathy. The results obtained were as follows.<BR>1. Ticarcillin was administered successfully at a daily dose of 6 to 16g in combination mainly with aminoglycoside antibiotics to 4 cases of suspected septicemia with underlying disease of acute myelogenous leukopenia (AML).<BR>2. Ticarcillin was administered successfully at a daily dose of 16 g in combination with CEZ and GM to 1 case of pneumonia due toEnterobacter andKlebsiella with AML.<BR>3. No noteworthy side effect of ticarcillin was observed, except eruption in 2 cases out of 10 cases in 7 patients treated.

Journal

  • CHEMOTHERAPY

    CHEMOTHERAPY 25 (9), 2540-2546, 1977

    Japanese Society of Chemotherapy

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