A case of intraoperative anaphylactic shock treated based on a guideline for anaphylactic reaction associated with antibiotics

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  • Sugime Fumiyuki
    Department of Anesthesiology, Sapporo Medical University School of Medicine
  • Sugino Shigekazu
    Department of Anesthesiology, Sapporo Medical University School of Medicine
  • Yamauchi Masanori
    Department of Anesthesiology, Sapporo Medical University School of Medicine
  • Iwasaki Sohshi
    Department of Anesthesiology, Sapporo Medical University School of Medicine
  • Nakayama Masayasu
    Department of Anesthesiology, Sapporo Medical University School of Medicine
  • Kanaya Noriaki
    Department of Anesthesiology, Sapporo Medical University School of Medicine
  • Namiki Akiyoshi
    Department of Anesthesiology, Sapporo Medical University School of Medicine

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Other Title
  • 抗菌薬投与に関連するアナフィラキシー対策のガイドラインに基づき治療しえた手術中のショックの１例

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We report a case of anaphylactic shock treated based on a clinical guideline for anaphylactic reaction asso. ciated with antibiotics under general anesthesia.<BR>A 63-year-old woman scheduled to undergo an excision of perianal Bowen's disease and a colostomy was given cefmetazole intravenously after induction of general anesthesia. Five minutes later, her systolic blood pressure decreased to 53 mmHg and erythema and edema appeared on her face and palms. Treatment based on the guideline was started immediately. She recovered from severe shock. Although the guideline is useful even in general anesthesia, it is important for anesthesiologists to interview patients regarding allergenic history, to observe skin symptoms carefully during administration, and to treat shock immediately.

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