書誌事項
- タイトル別名
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- Combined therapy with sulbactam/ampicillin and aztreonam for bacterial infections associated with hematological disease.
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説明
Combined antibacterial therapy with sulbactam/ampicillin (SBT/ABPC) and aztreonam (AZT) was given to 51 patients with infections associated with hematological disease. Among the 41 evaluable patients, 15 (36.6%) had acute leukemia, 18 (43.9%) malignant lymphoma, 6 (14.6%) multiple myeloma, 1 (2.4 %) myelodysplatic syndrome, and 1 (2.4%) chronic lymphocytic leukemia. The overall response to this treatment was 61.0%, and those for individual infections were 65.5% for suspected sepsis and 60.0% for pneumonia. The response was 66.7% for patients with acute leukemia, and 58.8% those with malignant lymphoma. In elderly patients, response is relatively low. Patients with neutropenia are resistant to current antibacterial therapy. No side effects of a high grade were seen in evaluable patients. This combination therapy is effective for various infections in patients with hematological malignancy.
収録刊行物
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- 日本化学療法学会雑誌
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日本化学療法学会雑誌 49 (5), 327-330, 2001
公益社団法人 日本化学療法学会
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詳細情報 詳細情報について
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- CRID
- 1390001206285775872
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- NII論文ID
- 130004298070
- 10006989931
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- NII書誌ID
- AN10472127
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- ISSN
- 18845886
- 13407007
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
