The drug susceptibility pattern of Streptococcus pneumoniae from pediatric sinusitis.

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  • 小児副鼻腔炎由来肺炎球菌の薬剤感受性パターン

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Abstract

We investigated the drug susceptibility pattern of Streptococcus pneumoniae and viridans streptococci from pediatric sinusitis that were obtained from October 1995 to June 1996. The results are summarized as follows;<BR>1. The frequency of detection of penicillin (PC)-intermediate S. pneumoniae (PISP)+PC-resistant S. pneumoniae (PRSP) was 49.6% in the 188 strains obtained, and that of PISP was high. The MIC distribution of drug susceptibility of cefditoren for PISP+PRSP was the lowest.<BR>2. The serovariants or serogroups of PSSP were widely distributed many serovariants, but those of PISP+PRSP were almost 19, 23 and 6 type.<BR>3. The frequency of detection of macrolides (MLs)-resistance of both PSSP and PISP+PRSP was high. And that of MLs-constitutive-resistant strains of PSSP and that of MLs-induced resistant strains of PISP+PRSP were high.<BR>4. The frequency of detection of multiple drug-resistant strains of Streptococcus oralis and Streptococcus mitis was high. The drug susceptibility patterns of those organisms were similar to that of S. pneumoniae.

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