書誌事項
- タイトル別名
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- Effects of Kabosu (Citrus sphaerocarpa Hort.) on Serum and Liver Cholesterol Levels in Rats.
- カボス ガ ラット ノ ケッセイ オヨビ カンゾウ コレステロール レベル ニ
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説明
We investigated the effects of Kabosu (Citrus sphaerocarpa Hort.) fractionated by several treatments on serum and liver cholesterol levels in rats. Kabosu fruits were pressed and separated into the Kabosu pomace (KP) fraction and juice. An ethanol precipitate (EP) fraction was obtained from 1l of juice by adding 0.71 l of ethanol. A hexane extract (HE) fraction was then obtained from EP by hexane extraction. The residue was designated the hexane residue (HR) fraction. In experiment 1, male SD strain rats aged 4 week were fed on a high-cholesterol diet supplemented with each fraction of Kabosu for 14 days. Serum and liver cholesterol levels were significantly decreased in the EP and HR groups. In experiment 2, rats were fed on a PCB (polychlorinated biphenyl) -containing diet supplemented with each fraction of Kabosu for 13 days. Serum and liver cholesterol levels were significantly decreased in the KP, EP and HR groups. In both of the experiments, when the fractions possessing the cholesterol-lowering activity were administered to rats, the amounts of excreted fecal bile acids and neutral sterols were increased. From these results, it is suggested that promotion of bile acid and neutral sterol excretion into feces is a possible mechanism for the cholesterollowering effect of Kabosu. We consider that the functional material is not fat-soluble because the cholesterollowering effect was not observed in the HE fraction.
収録刊行物
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- 日本栄養・食糧学会誌
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日本栄養・食糧学会誌 49 (6), 331-336, 1996
公益社団法人 日本栄養・食糧学会
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詳細情報 詳細情報について
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- CRID
- 1390001206291872768
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- NII論文ID
- 10009712790
- 10009282480
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- NII書誌ID
- AN00311992
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- ISSN
- 18832849
- 02873516
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- NDL書誌ID
- 4097357
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
