ラットの体重，血清コレステロールレベルおよび腎臓と精巣周囲の脂肪細胞に及ぼす乾燥酵母の影響

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  • Effects of Dried Yeast on the Body Weight, Serum Cholesterol Levels, and Perirenal and Periepididymal Adipose Tissue Cells in Rats.
  • ラット ノ タイジュウ ケッセイ コレステロール レベル オヨビ ジンゾウ ト

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The effects of dried yeast (DY) on body weight, serum cholesterol levels, and perirenal and periepididymal adipose tissue cells were studied in young and old rats. The rats were fed with 0% (control), 12.5% and 25% DY diets. In the 25% DY group, the body weights of young rats were lower than in the control group. A DY dose-dependent decrease in body weight was observed. No correlation was observed between change in body weight and food or water intake, and DY did not affect the body weight of old rats. The effects of DY on serum total cholesterol and HDL-cholesterol levels in young rats were less marked than those in old rats. However, serum total cholesterol and HDL-cholesterol levels in DY-fed old rats were significantly lower than those in the control rats, and this lowering effect was dependent on DY dose. The radius and volume of cells in periepididymal adipose tissue of DY-fed old rats were significantly higher than those in the control rats. The numbers of cells in periepididymal and perirenal adipose tissues in 25% DY-fed rats were lower than those in the control rats. It is concluded that dried yeast reduces body weight gain in young rats, and changes the serum cholesterol level and the radius, volume and number of cells in the periepididymal adipose tissue of old rats.

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