マウスへのヨーグルトおよびケフィール投与が腫ようの増殖に及ぼす影響

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  • Effects of orally administered yogurt and kefir on tumor growth in mice.
  • マウス エ ノ ヨーグルト オヨビ ケフィール トウヨ ガ シュヨウ ノ ゾウ

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The antitumor activity of yogurt and kefir was examined in BDF1 mice, weighing 17 to 19 g, which received a subcutaneaus inoculation of 7.2×105 cells of-Lewis lung carcinoma (3L-L) into the right axilla. The mice were fed by gastric intubation every day with a pasteurized solution of yogurt and kefir (freeze-dried base 2g/kg body weight) from day 1 to day 9 after tumor cell inoculation. The growth of 3 LL was inhibited by 62% and 46%, respectively, by oral administration of kefir and polysaccharide Kureha (PSK) as compared with non-treated mice. The weight of the spleen and the number of leucocytes in tumor-bearing mice on day 14 were increased 4-fold and 5-fold, respectively, as compared with normal mice. The increase was prevented by administration of kefir and PSK.

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