Effect of Ingestion of Supplements Containing Cystine and Cysteine Peptide Yeast Extract on Skin of Japanese Women: a Double-blind Randomized Controlled Trial

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  • シスチン・システインペプチド酵母エキス混合物含有サプリメントの摂取が女性の肌に及ぼす影響：二重盲検ランダム化比較試験
  • シスチン・システインペプチド酵母エキス混介物含有サプリメントの摂取が女性の肌に及ぼす影響 : 二重盲検ランダム化比較試験
  • シスチン ・ システインペプチド コウボ エキスコンカイブツ ガンユウ サプリメント ノ セッシュ ガ ジョセイ ノ ハダ ニ オヨボス エイキョウ : ニジュウ モウケンランダムカ ヒカク シケン

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[Objective] This study examined the effects of 12-week supplementation of cystine and cysteine peptide yeast extract on the skin of 22 Japanese women. [Method] This study was a double-blind, randomized controlled trial. Each of the 22 women was administered either cystine and cysteine peptide yeast extract or placebo for 12 weeks, and their skin conditions were evaluated every 4 weeks. [Result] Compared with the placebo group, the cystine and cysteine peptide yeast extract group (CC group) showed a significant reduction in skin redness (area Lv3) at week 4 relative to the baseline (p = 0.021) . [Conclusion] It is suggested that intake of cystine and cysteine peptide yeast extract has an ameliorative effect on skin redness. This study was approved by the institutional ethics committee and registered in the clinical trial registration system UMIN-CTR (UMIN000013167) .

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