Effects of Fibroin Foam Powder Prepared from Silk Yarn on Serum Cholesterol Concentration in Rats.

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  • Hirao Kazuko
    The United Graduated School of Agricultural Sciences, Iwate University
  • Tukakoshi Sachiko
    Department of Bioresourse Engineering, Faculty of Agriculture, Yamagata University
  • Igarashi Kiharu
    Department of Bioresourse Engineering, Faculty of Agriculture, Yamagata University

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Other Title
  • 絹フィブロイン起泡粉末の給与がラットの血清コレステロール濃度に及ぼす影響
  • キヌ フィブロイン キホウ フンマツ ノ キュウヨ ガ ラット ノ ケッセイ コレステロール ノウド ニ オヨボス エイキョウ

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Fibroin foam powder prepared from fibroin solution, which can be used as an ingredient in food to produce foam in sponge cake, was studied to examine its effects on serum cholesterol concentration in rats fed diets with or without cholesterol. The digestibility of fibroin foam powder in vitro was 11-25%. Addition of fibroin foam powder to a cholesterol-enriched diet lowered the serum total cholesterol level significantly. The total liver cholesterol in rats fed the cholesterol-enriched diet with fibroin foam powder tended to decrease in comparison with that in rats fed the cholesterol-enriched diet alone. The amounts of excreted bile acids were higher in the rats fed the cholesterol-free and -enriched diets with fibroin foam powder than in the rats fed the same diets without fibroin foam powder. Increases in the amounts of feces and fecal bile acids in the rats fed the fibroin foam powder suggest that the cholesterol-lowering effect of fibroin foam powder is due partly to promotion of bile acid excretion by its indigestible fraction.

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