Suppressive effect cyproheptadine on L-DOPA-induced growth hormone release in man(Note)

DOI Web Site Web Site PubMed オープンアクセス
  • NAKAI YOSHIKATSU
    Second Division, Department of Medicine, Kyoto University School of Medicine
  • IMURA HIROO
    Third Division, Department of Medicine, Kobe University School of Medicine

書誌事項

タイトル別名
  • Suppressive Effect of Cyproheptadine on L-DOPA-induced Growth Hormone Release in Man
  • Suppressive effect cyproheptadine on L

この論文をさがす

説明

In order to elucidate the relationship between dopaminergic and serotoninergic mechanisms in regulating secretion of human growth hormone (hGH), the effect of cyproheptadine, an antiserotoninergic agent, on 1-DOPA-induced hGH secretion was studied in normal subjects. Oral administration of 500 mg of 1-DOPA caused a rise in plasma hGH in 6 of 7 subjects studied. This rise in plasma hGH was significantly blunted by the intravenous infusion of 5 mg of cyproheptadine. These results suggest the close relationship between dopamine and serotonin in the control of hGH secretion.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ