Intrahypothalamic Implants of Testosterone or Dihydrotestosterone in Neonatal Female Rats with Reference to Induction of Sterility (Note)
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- HAYASHI SHINJI
- Endocrine Division, National Cancer Center Research Institute
書誌事項
- タイトル別名
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- Intrahypothalamic implants of testosterone or dihydrotestosterone in neonatal female rats with reference to induction of sterility.
- Intrahypothalamic Implants of Testoster
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抄録
Implants of paraffin micropellets containing about 5μg 5α-dihydrotestosterone (DHT) into the hypothalamus of 5-day-old female rats were without effect on the sexual differentiation of the brain. By contrast, approximately the same amount of testosterone propionate (TP) given as subcutaneous or intrahypothalamic micropellets masculinized the female brain. In the light of these results as well as the author's previous findings that an antiestrogen implanted into the hypothalamus of neonatal female rats failed to block masculinization by subcutaneous injection of TP, the possibility cannot be excluded that testosterone is capable of masculinizing the brain of neonatal females without being converted into estrogens.
収録刊行物
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- Endocrinologia Japonica
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Endocrinologia Japonica 24 (6), 595-599, 1977
一般社団法人 日本内分泌学会
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詳細情報 詳細情報について
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- CRID
- 1390001206299861760
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- NII論文ID
- 130000954879
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- NII書誌ID
- AA00635052
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- ISSN
- 21856370
- 00137219
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- NDL書誌ID
- 1916956
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- PubMed
- 606548
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可