A case of the Schoenlein-Henoch purpura with generalized seizures and high frequency of sister chromatoid exchanges.
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- NATORI Norihiko
- Nishitaga Byoin National Sanatorium
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- FURUYAMA Michiko
- Nishitaga Byoin National Sanatorium
Bibliographic Information
- Other Title
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- 高頻度の姉妹染色分体交換(Sister chromatoid exchange)とけいれん斑発作を合併したSchoenlein-Henoch紫斑病の1例
Abstract
A 13-year-old boy of the Schönlein-Henoch purpura with generalized seizures and high frequency of sister chromatoid exchanges is reported.<br>He suffered from abdominal pain and nausea in July 1986 and after a few days developed blepharoedema, facial exanthema, hematuria, bloody stool and generalized seizures.<br>He was admitted to our hospital on September 18, 1986. His family history was negative. Urinalysis revealed hematuria and proteinuria. EEG showed diffuse paroxysmal slow waves. Needle biopsy of a kidney revealed mesenchymal proliferation and deposits of IgA, IgM and fibrinogen. Chromosome analysis showed high frequency of sister chromatoid exchanges. His parent had high frequency, too.<br>It is not known why generalized seizures occur in the Schönlein-Henoch purpura.<br>This may be the first case report of the Schönlein-Henoch purpura that showed high frequency of sister chromatoid exchanges.<br>This suggest that etiology of generalized seizures may be associated with genetic factors.
Journal
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- Japanese Journal of National Medical Services
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Japanese Journal of National Medical Services 43 (11), 1211-1213, 1989
Japanese Society of National Medical Services
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Keywords
Details 詳細情報について
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- CRID
- 1390001206312858240
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- NII Article ID
- 130004107165
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- ISSN
- 18848729
- 00211699
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed