Analysis of prognostic factors of hepatocellular carcinoma after interventional angiography.

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  • 肝細胞癌におけるＩｎｔｅｒｖｅｎｔｉｏｎａｌ　Ａｎｇｉｏｇｒａｐｈｙ後の予後因子の解析

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Abstract

To make clear which factors are closely related with the survival period of patients with hepatocellular carcinoma (HCC) treated with one shot arterial infusion or trans-catheter arterial embolization, the authors studied on 70 cases of unresected HCC using Cox's proportional hazard model, and then evaluated cumulative survival rates and significant differences according to the available factors. The results were as follows. Among liver function tests, six items such as LAP, γ-GTP, ALP, total-Bil, γ-gl and Alb were efficient for the prediction of prognosis. The factors such as age, sex, AFP, HBsAg+ve were not useful. Cumulative size (occupation rate) of tumor, the degree of tumor thrombus in portal vein and tumor type were all useful factors. HCC located in medial segment was found to be less effective of interventional angiography than HCC located in other segments. adriamycin and trans-catheter arterial embolization were more beneficial than mitomycin C and one shot arterial infusion therapy.

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