放射線全身被曝による半致死線量（ＬＤ５０／６０）の推定　　広島の爆心地域調査から

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タイトル別名
  • The LD50/60 in man: An analysis of mortality of survivors exposed to Hiroshima A-bomb in the hypocenter area.
  • an Analysis of Mortality of Survivors Exposed to Hiroshima A-bomb in the Hypocenter Area
  • ―広島の爆心地域調査から―

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抄録

In Hiroshima and Nagasaki a large number of people were exposed to atomic bomb radiation under the war time conditions, but these data have not been used for the estimation of LD50 of man, because of the difficulty in separating mortalities caused by radiation itself from those caused by blast or heat.<br>Based on the retrospective survey of heavily A-bombed area of Hiroshima conducted by Hiroshima city authorities and members of the RINMB of Hiroshima University during the period of 1969 to 1976, there were 3, 215 persons who were exposed at distances of 500 to 1, 300 meters from the hypo center in the Japanese wooden houses. Of these, 1, 085 (33.7%) died on the day of the bombing, and the remaining 555 (26% of those surviving the first day) died during the following 60 days.<br>Our hypothesis was that the deaths on the first day were predominantly due to exposure to radiation itself and, therefore, the data obtained from our survey were suitable for an estimate of the LD50/60 in humans under the war time conditions. Thus, the distance at which the mortality was 50% was calculated from the curve of probability of deaths at various distances for the above persons who died between 2 to 60 days after the bombing. This distance was 903±8 meters. The parameters required for the conversion of this distance to radiation dose will not be available until the end of 1987 because of the reassessment of A-bomb radiation dose, which is in progress. Age and sex differences in exposed distances for LD50/60 were also examined. Namely, lethal effects of radiation exposure were somewhat higher in the population with over 50 years of age, and lower in females with under 40 years of age.

収録刊行物

  • 医療

    医療 41 (6), 499-505, 1987

    一般社団法人 国立医療学会

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