The Steroid-Diabetes in Patients of Blood Diseses

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  • 血液疾患におけるステロイド糖尿病について
  • ケツエキ シッカン ニ オケル ステロイド トウニョウビョウ ニ ツイテ

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Abstract

Among the blood diseases, what may be the indication for the corticosteroid-therapy were chosen.<br>1) The occurence of diabetes mellitus were 5 out of 9 patients in aplastic anemia, 1 out of 9 in acute leucemia, null out of 4 in the others, totally 6 out of 22.<br>2) Among the 6, 4 had received long-termed steroid-therapy by the time of the onset of diabetes mellitus, the remaining two (both were patients of aplastic anemia), however, had received none.<br>3) About the remaining two, the onset of diabetes mellitus was coincident with the onset of serum hepatitis following the blood transfusions.<br>4) All the 6 had received repeated blood transfusions, and moreover all revealed the disturbances of hepatic functions.<br>From the above observations, it was concluded that diabetes mellitus in patients of blood diseases, esp. of aplastic anemia might be manifested by not only the long-termed corticosteroid-therapy but more significantly the disturbances of hepatic functions. As the cause of the hepatic damage, the serum hepatitis following blood transfusions was emphasized.

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