Studies on the tuberculin reactivity of tuberculin-active peptide

SOMEYA Shiro, KOYAMA Kenjiro, ASAMI Nozomu, KATAOKA Tetsuo, YAMAMURA Yuichi

doi:10.1111/j.1348-0421.1966.tb00311.x

Studies on the tuberculin reactivity of tuberculin-active peptide

DOI Web Site Web Site Web Site 被引用文献1件参考文献4件

SOMEYA Shiro

Department of Microbiology, Institute of Public Health Department of Tuberculosis, National Institute of Health Department of Internal Medicine, University of Osaka School of Medicine
KOYAMA Kenjiro

Department of Microbiology, Institute of Public Health Department of Tuberculosis, National Institute of Health Department of Internal Medicine, University of Osaka School of Medicine
ASAMI Nozomu

Department of Microbiology, Institute of Public Health Department of Tuberculosis, National Institute of Health Department of Internal Medicine, University of Osaka School of Medicine
KATAOKA Tetsuo

Department of Microbiology, Institute of Public Health Department of Tuberculosis, National Institute of Health Department of Internal Medicine, University of Osaka School of Medicine
YAMAMURA Yuichi

Department of Microbiology, Institute of Public Health Department of Tuberculosis, National Institute of Health Department of Internal Medicine, University of Osaka School of Medicine

書誌事項

タイトル別名

Studies on the Tuberculin Reactivity of Tuberculin-Active Peptide<sup>1</sup>
Studies on the Tuberculin Reactivity of Tuberculin‐Active Peptide

この論文をさがす

抄録

A comparative study of the tuberculin potency and reactivity to TAP and PPD-S was made in humans and guinea pigs. A comparison of reactions elicited by TAP and PPD-S was made in two groups of guinea pigs previously inoculated with killed bacilli or with living bacilli. The tuberculin reactions produced by TAP and PPD-S in human beings was studied in school children from rural districts. These children were divided randomly into three groups and each group was given a different amount of TAP and PPD-S. The results obtained are as follows: (1) While relative potency of TAP was relatively much weaker than PPD-S in guinea pigs sensitized with tubercle bacilli, in human beings the tuberculin potency of TAP was approximately 1/2 or 1/3 that of PPD-S. (2) There was a marked difference in the tuberculin reactivity to TAP and PPD-S between guinea pigs immunized with killed bacilli and guinea pigs immunized with living bacilli.