Penicillin Resistance Correlated With Phage Types in Staphylococcus aureus
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- FUJISAWA Hiroyasu
- Department of Surgery I, Gunma University School of Medicine
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- ISHIHARA Keizo
- Department of Surgery I, Gunma University School of Medicine
Bibliographic Information
- Other Title
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- Penicillin Resistance Correlated with Phage Types in <i>Staphylococcus aureus</i>
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Abstract
The resistance of Staphylococcus aureus to penicillin G was studied quantitatively by the dilution method. A series of 338 strains obtained from patients fell into 3 groups according to degree of resistance; 150 highly resistant strains, 137 moderately resistant strains, and 51 sensitive strains. Furthermore, 287 strains resistant to 0.2 units per ml or more of penicillin fell into 2 groups according to antibiotic resistance pattern, 173 single resistant strains and 114 multiple resistant strains. The vast majority of the highly resistant strains belonged to phage-groups I and III, whereas the majority of the moderately resistant strains belonged to group II. Of the highly resistant strains, 65% were multiple resistant, and 35% single resistant. Of the multiple resistant strains, 86% belonged to the 52, 52A, 80, 81 complex within group I and to group III, but none belonged to group II. Of the strains that were highly resistant to penicillin only, 83% belonged to group I, and of these, nearly one-half were members of the 52, 52A, 80, 81 complex, and the other half belonged to the rest of phage-types within group I. In contrast, 88% of the moderately resistant strains were single resistant, and of these, 58% belonged to group II. Mercury resistance was observed in 77% of the highly resistant strains of the multiple resistance pattern, 29% of those of the resistance to penicillin alone and 3% of the strains moderately resistant to penicillin alone. Of the mercury resistant strains, 68% belonged to the 52, 52A, 80, 81 complex, 3% to the rest of phage-types in group I, 12% to group III, but none belonged to group II. The results suggest that there may exist a difference in the mechanisms of inactivating penicillin between strains of staphylococci highly resistant and moderately resistant to penicillin.
Journal
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- Japanese Journal of Microbiology
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Japanese Journal of Microbiology 12 (1), 1-6, 1968
Center For Academic Publications Japan
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Details 詳細情報について
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- CRID
- 1390001206319434496
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- NII Article ID
- 130004690739
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- NII Book ID
- AA00246855
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- COI
- 1:STN:280:DyaF1cvgtFOqtA%3D%3D
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- NDL BIB ID
- 8511543
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- ISSN
- 00215139
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- PubMed
- 4233901
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- Web Site
- http://id.ndl.go.jp/bib/8511543
- https://ndlsearch.ndl.go.jp/books/R000000004-I8511543
- https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1348-0421.1968.tb00363.x
- https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1348-0421.1968.tb00363.x
- https://search.jamas.or.jp/link/ui/1969023153
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed