REDUCTION OF GLYOXYLATE BY LACTATE DEHYDROGENASE

  • 沢木 〓二
    Department of Internal Medicine, Faculty of Medicine, Nagoya University
  • 服部 尚興
    Department of Internal Medicine, Faculty of Medicine, Nagoya University
  • 山田 弘三
    Department of Internal Medicine, Faculty of Medicine, Nagoya University

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Reduction of glyoxylate by lactate dehydrogenase was confirmed through the demonstration of the formation of reaction products, mode of inhibition by trypsin and urea, and the mode of distribution among different organs. In crystalline lactate dehydrogenase, the difference in Km and pH was clearly demonstrated between glyoxylate and pyruvate.

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