Study on Optimal Fat Content in Total Parenteral Nutrition in Partially Hepatectomized Rats.
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- ABE Shun-ichi
- Research Division, The Green Cross Corporation
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- SAKABE Shin-ichi
- Research Division, The Green Cross Corporation
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- HIRATA Mitsuru
- Research Division, The Green Cross Corporation
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- KAMURO Hideki
- Research Division, The Green Cross Corporation
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- ASAHARA Naomi
- Research Division, The Green Cross Corporation
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- WATANABE Masahiro
- Research Division, The Green Cross Corporation
書誌事項
- タイトル別名
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- Study on Optimal Fat Content in Total P
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In order to investigate the optimal fat content for total parenteral nutrition (TPN) solutions, male Wistar rats were subjected to 70% hepatectomy and then placed, for five days, on one of five TPN regimens in which fat represented 0%, 10%, 20%, 30% and 40%, respectively, of the total calorie content. As serum triglyceride levels in the fat-treated groups were lower than those in the non-treated normal rats, it was concluded that the administered fat was sufficiently hydro-lyzed. The greater the fat content, the higher the regeneration rate of the remnant liver. Significant differences were found between the 0%-fat group and 20%-plus fat groups. Hepatic triglyceride level was signifi-cantly lower in the 20%-fat group. Hepatic protein level was significantly elevated in all fat-treated groups. Serum phospholipids and total choles-terol due to the lecithin contained in fat emulsion were significantly elevated in the 30 and 40%-fat groups, indicating that fat content of 30 and 40% was excessive. The results suggest that TPN containing fat is superior to fat-free TPN for liver regeneration after partial hepatectomy, and that optimal fat content is estimated to be about 20% of total calorie content in the case of this fat emulsion.
収録刊行物
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 43 (2), 187-198, 1997
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詳細情報 詳細情報について
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- CRID
- 1390001206322891264
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- NII論文ID
- 130001370271
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- NII書誌ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 4231093
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- PubMed
- 9219092
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- PubMed
- CiNii Articles
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