Transport of vitamin B6 in human erythrocytes-2-Effects of incubation temperature,glycolytic inhibitor and vitamin B6 analogues on transport of vitamin B6 in human erythrocytes
書誌事項
- タイトル別名
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- Transport of Vitamin B<sub>6</sub> in Human Erythrocytes
- Transport of Vitamin B6 in Human Erythrocytes
- II. Effects of Incubation Temperature, Glycolytic Inhibitor and Vitamin B<sub>6</sub> Analogues on Transport of Vitamin B<sub>6</sub> in Human Erythrocytes
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Lowering incubation temperature resulted in a marked decreased transport of pyridoxine and pyridoxamine and a slightly decreased one of pyridoxal. Potassium fluoride inhibited the transport of pyridoxine, pyridoxamine and pyridoxal phosphate into the cells by 20, 15 and 60%, respectively, whereas the transport of pyridoxal was not inhibited. The conversion of pyridoxal to pyridoxal phosphate in the cells was also inhibited by the addition of potassium fluoride.<br>In the presence of deoxypyridoxine, the transport of pyridoxine and pyridoxamine into the cells was inhibited, while that of pyridoxal and pyridoxal phosphate was not. Further, pyridoxal phosphate concentrations in the cells after incubation with free forms of B6 were decreased in the presence of deoxypyridoxine. Deoxypyridoxine phosphate did not inhibit the transport of various forms of B6.<br>These evidences lead to the conclusion that the transport process of various forms of B6 and their phosphorylation in erythrocytes are associated with the energy produced by intracellular glycolysis.
収録刊行物
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- THE JOURNAL OF VITAMINOLOGY
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THE JOURNAL OF VITAMINOLOGY 16 (3), 237-242, 1970
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詳細情報 詳細情報について
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- CRID
- 1390001206323098624
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- NII論文ID
- 130001749505
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- NII書誌ID
- AA00247734
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- COI
- 1:CAS:528:DyaE3MXhvV2l
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- NDL書誌ID
- 8506313
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- ISSN
- 00225398
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- PubMed
- 5507133
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可