らい菌の微細構造に関する細胞生物学的研究

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タイトル別名
  • Cyto-morphological Study of Leprosy Bacilli in the Host Cell
  • ライキン ノ ビサイ コウゾウ ニ カンスル サイボウ セイブツガクテキ ケン

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説明

Electron microscopical studies on the cellular organelle of M. leprae were done in comparative cyto-morphological method. The outlines of main subjects were briefly described below. <br>1. Peripheral parts of the bacilli The peripheral parts of the bacilli were divided into 3 layers; (a) the capsular struc- ture, (b) the cell wall, and (c) the cytoplasmic membrane. The capsular structure of M. leprae was more thin than that of M. lepraemurium.<br>2. Intra-cytoplasmic organelle In cytoplasm of the bacilli, two kinds organelle-the intracellular membranous orga- nelle (mesosomes) and the electron-dense or -homogenous grnules-were found typically.<br>3. Cell division process In active bacilli, the mesosomes were observed generally at or near the cell divisionn site, and they seemed to play the significant role in cell division process.<br>4. Other organelle in Lepra-cell The large electron-dense and -homogenous bodies were found outside the bacilli, and in these bodies the small electron-dense granules were observed. It was assumed that these bodies were originated from the bacilli and "L-form theory" or "Life cycle hypothesis" was adopted for explaining their exsistences and organisations. Further investigation should be made in the future on this problem.

収録刊行物

  • レプラ

    レプラ 44 (3), 163-176, 1975

    日本ハンセン病学会

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