Examination of the structure of an unknown green fluorescent compound, compound G2, accumulated in non-growing cells of Eremothecium ashbyii by the addition of dimeric diacetyl.
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- MITSUDA Hisateru
- Laboratory of Nutritional Chemistry, Faculty of Agriculture, Kyoto University
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- NAKAJIMA Kenji
- Laboratory of Nutritional Chemistry, Faculty of Agriculture, Kyoto University
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- YAMADA Yukiko
- Laboratory of Nutritional Chemistry, Faculty of Agriculture, Kyoto University
Bibliographic Information
- Other Title
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- Examination of the structure of an unkn
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Abstract
The addition of dimeric diacetyl to Eremothecium ashbyii caused simultaneous accumulation of two green fluorescent compounds with the inhibition of riboflavin formation in non-growing cells. One compound, referred to as Compound G1, was identified as 6, 7-dimethyl-8-ribityllumazine as reported previously and the other is referred to as Compound G2. The latter compound was considered to be 6-methyl-7-(2-hydroxy-2-methyl-3-oxobutyl)-8-ribityllumazine because a violet fluo-rescent compound, 6-methyl-7-hydroxy-8-ribityllumazine was derived from Compound G2 in the presence of p-quinone and because the known action mechanism of dimeric diacetyl as a trapping agent of possible intermediates in the biosynthetic pathway.<br> The results indicate that an immediate intermediate to 6, 7-dimethyl-8-ribityllumazine in the biosynthetic pathway of riboflavin is 4-ribitylamino-5-amino-2, 6-dihydroxypyrimidine, whose pyrimidine portion is derived by the elimination of a dimeric diacetyl fragment from the molecule of the isolated lumazine.
Journal
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 23 (5), 413-422, 1977
Center for Academic Publications Japan
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Details 詳細情報について
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- CRID
- 1390001206324989696
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- NII Article ID
- 130001372252
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- NII Book ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL BIB ID
- 1913608
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- PubMed
- 564400
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed