Kaempferia parviflora Extract Increases Whole-Body Energy Expenditure in Humans : Roles of Brown Adipose Tissue
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- MATSUSHITA Mami
- Department of Nutrition, School of Nursing and Nutrition, Tenshi College
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- YONESHIRO Takeshi
- Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University
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- AITA Sayuri
- Department of Food and Nutrition, Hakodate Junior College
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- KAMIYA Tomoyasu
- Research and Development Division, Toyo Shinyaku Co. Ltd.
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- KUSABA Nobutaka
- Research and Development Division, Toyo Shinyaku Co. Ltd.
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- YAMAGUCHI Kazuya
- Research and Development Division, Toyo Shinyaku Co. Ltd.
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- TAKAGAKI Kinya
- Research and Development Division, Toyo Shinyaku Co. Ltd.
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- KAMEYA Toshimitsu
- LSI Sapporo Clinic
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- SUGIE Hiroki
- LSI Sapporo Clinic
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- SAITO Masayuki
- Department of Nutrition, School of Nursing and Nutrition, Tenshi College
書誌事項
- タイトル別名
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- <i>Kaempferia parviflora</i> Extract Increases Whole-Body Energy Expenditure in Humans: Roles of Brown Adipose Tissue
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抄録
Kaempferia parviflora extract (KP) has been reported to have a preventive effect on obesity in mice, probably by increasing energy expenditure (EE). The aims of the current study were to examine the acute effects of KP ingestion on whole-body EE in humans and to analyze its relation to the activity of brown adipose tissue (BAT), a site of non-shivering thermogenesis. After an oral ingestion of an ethanol extract of KP, EE increased significantly, showing a maximal increase of 229±69 kJ/d at 60 min, while it did not change after placebo ingestion. To evaluate BAT activity, the subjects underwent fluorodeoxyglucose-positron emission tomography, and divided into two groups with high- and low-BAT activities. A similar and greater response of EE to KP ingestion was observed in the high-BAT group (351±50 kJ/d at 60 min), but not in the low activity group. Placebo ingestion did not cause any significant EE change in either group. These results indicate that a single oral ingestion of the KP extract can potentially increase whole-body EE probably through the activation of BAT in healthy men, and may be useful as an anti-obesity regimen.
収録刊行物
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 61 (1), 79-83, 2015
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詳細情報 詳細情報について
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- CRID
- 1390001206325240832
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- NII論文ID
- 130005070826
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- NII書誌ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 026193523
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- PubMed
- 25994142
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可