Effect of Dietary Amino Acids on Behavior and Serum Levels of Amino Acids in Stress Loaded Rats.
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- KITAJIMA Hideaki
- Laboratory of Nutritional Biochemistry, School of Food and Nutritional Sciences. University of Shizuoka Pharmacological Evaluation Laboratory, Self Medication Laboratories, Taisho Pharmaceutical Co., Ltd.
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- SHIOMOTO Hidemi
- Pharmacological Evaluation Laboratory, Self Medication Laboratories, Taisho Pharmaceutical Co., Ltd.
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- OSADA Kazumi
- Pharmacological Evaluation Laboratory, Self Medication Laboratories, Taisho Pharmaceutical Co., Ltd.
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- YOKOGOSHI Hidehiko
- Laboratory of Nutritional Biochemistry, School of Food and Nutritional Sciences. University of Shizuoka
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Interrelationships between behavior and concentrations of serum amino acids in stressed rats with immobilization and water immersion were investigated. Rats were subjected to 7h of immobilization with water-immersion stress (IWS) in each sequential day, and serum amino acids were then determined. On the first day, serum taurine, threonine, valine, leucine, isoleucine, phenylalanine, lysine, and histidine (increased-type of amino acids) were significantly increased, but alanine (decreased-type) was significantly de-creased. On days 3 and 7, the increase was retained, except for threonine, histidine, and ly-sine. Spontaneous activities (locomotion, rearing behavior, hole-poking) under loading water-immersion stress were significantly decreased, but a supplementation of branchedchain amino acids (BCAA) led to recovery. We suggest that pretreatment with some kind of increased type of amino acid, such as BCAA, might effectively prevent decline in spontaneous activities evoked by water-immersion stress.
収録刊行物
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 48 (3), 194-200, 2002
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詳細情報 詳細情報について
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- CRID
- 1390001206325249408
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- NII論文ID
- 130001377114
- 50000585327
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- NII書誌ID
- AA00703822
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 6250590
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- PubMed
- 12350077
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可