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- SHIM Jae Eun
- Department of Food and Nutrition, Seoul National University Research Institute of Human Ecology, Seoul National University
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- PAIK Hee Young
- Department of Food and Nutrition, Seoul National University Research Institute of Human Ecology, Seoul National University
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- SHIN Chan Soo
- Department of Internal Medicine, Seoul National University College of Medicine
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- PARK Kyong Soo
- Department of Internal Medicine, Seoul National University College of Medicine
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- LEE Hong Kyu
- Department of Internal Medicine, Eulji University Medical College
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This study was performed to investigate the relationship between serum L-ascorbic acid, vitamin C intake, and diabetes in a nested case-control study. A cross-sectional survey of diet and health was conducted in 2,048 adults with an age of 30 y or older in Yonchon County, Korea. An oral glucose tolerance test was administered to all participants. One hundred cases of newly diagnosed diabetes were identified. Two healthy controls for each case matched with age, gender, drinking status, and smoking status were selected among the survey participants. L-Ascorbic acid levels were analyzed in fasting serum samples and one 24-h dietary recall was performed. Dietary vitamin C intake of persons with diabetes was 50.1±47.6 mg/d and that of controls was 55.1±41.1 mg/d. People with diabetes (22.3±16.8 μmol/L) have lower serum ascorbic acid levels than their controls (26.3±17.0 μmol/L) and the difference was significant by paired t-test (p<0.01). The association between diabetes and serum ascorbic acid level was still significant in non-smokers (24.2±17.8 μmol/L for the diabetes group and 29.5±16.7 μmol/L for the control group, p<0.01) but not in smokers (19.4±15.7 μmol/L for the diabetes group and 21.2±16.0 μmol/L for the control group). Our results suggest that diabetes and smoking interactively affect serum ascorbic acid levels. Since this population had poor nutritional status of vitamin C, further investigation of association between serum ascorbic acid level and diabetes and smoking by the level of vitamin C consumption is warranted.
収録刊行物
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- Journal of Nutritional Science and Vitaminology
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Journal of Nutritional Science and Vitaminology 56 (4), 217-221, 2010
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詳細情報 詳細情報について
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- CRID
- 1390001206325403264
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- NII論文ID
- 10026569791
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- NII書誌ID
- AA00703822
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- COI
- 1:CAS:528:DC%2BC3cXhtFensrrL
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- ISSN
- 18817742
- 03014800
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- NDL書誌ID
- 10793683
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
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- 抄録ライセンスフラグ
- 使用不可