妊娠家兎の卵胞破壊が妊娠維持に及ぼす影響

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  • The effect of destruction of ovarian follicles in pregnant rabbits on the maintenance of pregnancy.
  • 妊娠家兎の卵胞破壊が妊娠維持に及ぼす影響〔英文〕
  • ニンシン カト ノ ランポウ ハカイ ガ ニンシン イジ ニ オヨボス エイキ

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Effects of destruction of follicles (by cauterization or puncture) or ovaries (by resection) on maintenance of pregnancy were examined in pregnant rabbits which received unilateral ovariectomy (ULO) on day 23 of pregnancy.<BR>Normal delivery was produced after ULO in 2 of 3 pregnant does. Pregnant does which received ULO aborted completely after destruction of all visible follicles (≥ 1.0 mm in diameter) in residual ovaries by cauterization or puncture. Fewer than 2 corpora lutea or 10 large follicles (≥ 1.5 mm in diameter) in residual ovaries of pregnant does which received ULO could not maintain pregnancy. Resection of more than one-third of the residual ovary also resulted in abortion.<BR>Plasma progesterone levels in pregnant does which received ULO decreased after follicular or ovarian destruction. The levels after treatment in does with normal delivery were significantly higher than those in does which aborted. Minimal concen-tration of progesterone for maintenance of pregnancy seemed to be about 5 ng/ml in peripheral plasma on day 23 of pregnancy.

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