過排卵家兎血中プロゲステロン及びPGF2α値の変化と卵移動

堤 義雄, 武田 哲男, 鈴木 裕之, 岩崎 有紀, 稲田 和義, 南 豊晴

doi:10.1262/jrd1977.26.15

Concentrations of peripheral serum progesterone and prostaglandin F_2α (PGF_2α) in superovulated and normally mated rabbits were determined before and after mating by radioimmunoassay. Multiple vaginal washings were also conducted to recover eggs expelled into the vagina of superovulaed rabbits. The correlation between the fluctuations of progesterone and PGF_2α levels and egg transport in superovulated does was discussed. The concentration of progesterone remained at low levels before mating, however a temporary increase was seen 10 hours post coitum (p.c.) and a decrease was noted 24 hours p.c. in both normally ovulated and superovulated rabbits. After 36 hours p.c. the levels gradually increased in normally ovulated does, while the levels in su-perovulated does were sharply elevated to reach an equilibrium 78 hours p.c., except for depressions of the levels at 66 and 96 hours p.c. Maximum values were observed at 120 hours p.c. in superovulated rabbits. During the period of this sharp elevation in progesterone levels, 74.7% of eggs which were recovered from the vagina of super-ovulated does were obtained. The concentration of PGF_2α in superovulated does showed no significant variations before and after injections of PMSG and HCG, and the levels were relatively constant ranging from 0.8 to 3.7 ng/ml. However, the levels of PGF_2α in normally ovulated rabbits greatly varied with time, and it was difficult to discuss their trends. It was assumed that the expulsion of a number of eggs in superovulated rabbits into the vagina may be due to the post coital sharp elevation of progesterone levels in blood of superovulated does.

過排卵家兎血中プロゲステロン及びPGF<SUB>2α</SUB>値の変化と卵移動

書誌事項

この論文をさがす

抄録

収録刊行物

詳細情報詳細情報について

書き出し

問題の指摘