腹腔内投与したカリフラワーレクチンのマウスの成長と脂質代謝へ与える影響

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タイトル別名
  • Effects of an Intraperitoneally Administered Cauliflower Lectin on the Growth and Lipid Metabolism of Mice.
  • 腹腔内投与したカリフラワーレクチンのマウスの成長と脂質代謝へ与える影響〔英文〕
  • フククウナイ トウヨシタ カリフラワー レクチン ノ マウス ノ セイチョウ

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抄録

A lectin was isolated from rapidly boiled cauliflower, Brassica oleracea var. botrys, and partially purified by DEAE-cellulose column chromatography. The boiled cauliflower had higher hemagglutinating activity than the fresh vegetable.<BR>The cauliflower lectin was intraperitoneally injected to mice weighing approximately 20 g. The injection of this lectin resulted in growth retardation and a decline in the intestinal enzyme activity. A decrease in plasma lipids was also observed, together with the promotion of lipid peroxidation in various tissues.<BR>These results indicate that, when the heat-stable cauliflower lectin was administered by injection, growth inhibition, a decline in villus enzyme activity and increased catabolic breakdown of body lipids occured in mice. The mechanism for the toxicity of this cauliflower lectin resembles that of a bean lectin ingested orally.

収録刊行物

  • 日本家政学会誌

    日本家政学会誌 45 (8), 673-680, 1994

    一般社団法人 日本家政学会

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