Neuroendocrine Mechanisms Regulating Pulsatile Luteinizing Hormone Secretion

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  • TSUKAMURA Hiroko
    Laboratory of Animal Reproproduction, School of Agricultural Sciences, Nagoya University

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  • 黄体形成ホルモンのパルス状分泌を制御する中枢機構
  • 黄体形成ホルモンのパルス状分泌を制御する中枢機構(1995年度島村賞受賞講演論文)
  • オウタイ ケイセイ ホルモン ノ パルスジョウ ブンピ オ セイギョスル チュ

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Abstract

Pulsatile LHRH/LH secretion plays a key role in the maintainance of reproductive functions in mammals. The present study suggests that LHRH pulse generator is located in the anterior part of the mediobasal hypothalamus and consists of non-LHRH neurons. Environmental stimuli, such as suckling stimulus and fasting stress profoundly suppresses pulsatile LH secretion. The neural pathway involved in suckling- or fasting-induced suppression of LH pulses was discussed.<br>

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