咬合高径減少に伴うラット咬筋筋紡錘応答特性

  • 藤田 紘一
    東京医科歯科大学大学院医歯学総合研究科 口腔機能再構築学系専攻 口腔機能発育学講座 咬合機能矯正学分野

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タイトル別名
  • Response Properties of Jaw-closing Muscle Spindle during Decreased Occlusal Vertical Dimension in Rats
  • コウゴウ コウケイ ゲンショウ ニ トモナウ ラット コウキン キンボウスイ オウトウ トクセイ

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抄録

The masseter-muscle spindle is regarded as being highly adaptable to increases in the occlusal vertical dimension (iOVD), it is hypothesized that spindle function would adapt to a decrease in occlusal vertical dimension (dOVD) as well. Seventy-five 5-week-old female Wistar rats were divided into Control (n = 25) and Experimental (n = 50) groups ; those in the Experimental group received a 2.0-mm composite resin build-up to the maxillary molars. The Experimental group was divided into the resin-removal group (n = 25, build-up resin was removed) and the non resin-removal group (n = 25) 8 weeks later ; i. e., when the animals were 13 weeks old. Electrophysiological recordings were obtained from masseter-muscle spindle afferents in 13, 14, 15, 19, 21-week-old rats (n = 5 rats each) under general anesthesia. Masseter-muscle spindle sensitivity was significantly lower in the resin-removal group 1 week after resin-removal and for the rest of the observation period. The present results indicate that masseter-muscle spindles may not completely adapt to dOVD and may affect jaw function.

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