Pathological Diagnoses of Uterine Cervical Lesions Diagnosed as AGC on the Bethesda System 2001

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  • Kanuma Tatsuya
    Department of Gynecologic Oncology, Gunma Prefectural Cancer Center
  • Kigure Keiko
    Department of Gynecologic Oncology, Gunma Prefectural Cancer Center
  • Nishimura Tosio
    Department of Gynecologic Oncology, Gunma Prefectural Cancer Center
  • Ibuki Yuji
    Department of Gynecologic Oncology, Gunma Prefectural Cancer Center
  • Tsuchida Shigeru
    Department of Pathology, Gunma Prefectural Cancer Center
  • Kamiyama Harumi
    Department of Pathology, Gunma Prefectural Cancer Center
  • Iijima Misa
    Department of Pathology, Gunma Prefectural Cancer Center
  • Nakamura Kazuto
    Department of Gynecologic Oncology, Gunma Prefectural Cancer Center

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Other Title
  • 子宮頸部細胞診断基準ベセスダシステムにおけるAGCの臨床病理
  • シキュウ ケイブ サイボウ シンダン キジュン ベセスダ システム ニ オケル AGC ノ リンショウ ビョウリ

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Abstract

The Diagnostic criteria of AGC in Bethesda system includes broad spectrum pathological diagnoses. Forty-two cases diagnosed as AGC on Pap test were referred to our hospital over a period of four years. Almost half of AGC cytology was precancerous or early stage cancer, and about 30% of cases were invasive cancer. Only a quarter of the cases were normal or benign lesions. The glandular cell atypia of Pap smear included broad spectrum lesions in contrast to diagnostic criteria of squamous lesions. We should not hesitate to perform cone biopsy or more invasive surgery on cases in which confirmation of histological diagnosis is difficult.

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