MR画像を使用した脳血流SPECT減弱補正法の検討

  • 水野 啓志
    医療法人医人会中村記念病院放射線部
  • 高橋 正昭
    医療法人医人会中村記念病院放射線部 金沢大学大学院医学系研究科保健学専攻量子医療技術学講座
  • 金田 明義
    東芝医用システムエンジニアリング株式会社ソフトウェア技術部

書誌事項

タイトル別名
  • Evaluation of an Attenuation Correction Method in Brain Perfusion Single Photon Emission Computed Tomography Using Magnetic Resonance Imaging
  • MR ガゾウ オ シヨウ シタ ノウ ケツリュウ SPECT ゲン ジャク ホセイホウ ノ ケントウ

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説明

Generally, the Chang method depends on counts for the attenuation correction (AC) method in brain perfusion single-photon emission computed tomography (SPECT), because the head outlined for a uniform attenuation coefficient map is set to the sinogram of the projection data by the threshold (Sinogram Threshold Chang method). Magnetic resonance imaging (MRI) is a routine examination in our hospital. Patients who underwent N-isopropyl-p-[123I] iodoamphetamine (123I-IMP) SPECT are undergoing MRI. Therefore, we thought it help AC accuracy to set an accurate head outline by using the image. We jointly made “Software for an attenuation coefficient map using MRI” for trial purposes. This paper investigated whether the AC method using MRI promotes the accuracy of brain perfusion SPECT in some clinical samples. With AC methods using gamma ray transmission computed tomography (TCT) or X-ray CT (CT) also being taken into account, the AC method using MRI was compared with the Sinogram Threshold Chang method. As a result, count dependency was excluded by an accurate head outline setting that used MRI, and the AC method using MRI approached the effect of the AC method using TCT and CT more than the Sinogram Threshold Chang method. Therefore, it is suggested that the AC method using MRI is useful for the accuracy of brain perfusion SPECT.

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